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Dieter Rehder
Bioinorganic Vanadium Chemistry

Vanadium is named after Vanadis, the most aristocratic of Norse goddesses, who symbolises beauty and fertility – essential features of vanadium chemistry It is a ubiquitous trace element, with a surprising range of biological functions In Bioinorganic Vanadium Chemistry, Dieter Rehder addresses the major aspects of vanadium chemistry related to living organisms and the mutual impact between biological and inorganic vanadium chemistry

Frederick R Maxfield, James M Willard, Shuyan Lu
Lysosomes: Biology, Diseases, and Therapeutics

Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development

• Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates
• Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair
• Introduces new pathways in therapeutic development and new mechanisms in drug development

Continuous-Flow Chemistry in the Research Laboratory: Modern Organic Chemistry in Dedicated Reactors at the Dawn of the 21st Century

Authors: Glasnov, Toma
A comprehensive but compact overview on the existing literature in the field from the last 15 years, covering the beginnings and evolution of this area of research
Quick reference guide for broad area of synthetic organic chemists with interests in new technology both at universities as well as in industry
Easy to read work intended to inspire also newcomers to become practitioners

This book presents a short introduction to the historical background to the field, the state of the art and a brief survey of the available instrumentation and the processing techniques used The following major areas of interest in synthetic, organic and medicinal chemistry are elaborated on: transition-metal catalyzed reactions, organocatalytic transformations, heterocyclic synthesis, and photochemical reactions Finally, selected applications in industry are also discussed With its ample presentation of examples from recent literature, this is an essential and reliable source of information for both experienced researchers and postgraduate newcomers to the field

Marcel Gielen, Rudolph Willem, Bernd Wrackmeyer
Advanced Applications of NMR to Organometallic Chemistry

This new series offers leading contributions by well known chemists reviewing the state-of-the-art of this wide research area Physical Organometallic Chemistry aims to develop new insights and to promote novel interest and investigations applicable to organometallic chemistry

NMR spectroscopy has had a considerable impact on many fields of chemistry, although it has served organometallic chemistry mainly on a routine level In a collection of reviews, leading chemists provide an insight into the scope of applications and uncover the potential of this technique for organometallic chemists Advanced Applications of NMR to Organometallic Chemistry;
* Illustrates how recent 1D and 2D and specialized multinuclear applications can solve specific problems encountered by organometallic chemists
* Surveys modern NMR techniques in organometallic chemistry
* Includes metal NMR related techniques
* Focuses on the advent of solid state NMR in organometallic chemistry
This book will prove invaluable to the NMR spectroscopist and organometallic chemists and will also be of interest to all organic, inorganic and physical chemists Contents: Selective Excitation and Selective Detection in ?29Si NMR; Two-dimensional ?13C, Metal Nuclei Correlation; Two-dimensional ?1H-?119Sn Proton Detected Correlation Spectroscopy in Coordination Chemistry of Hypervalent Organotin Compounds; Indirect Nuclear ?119Sn-X Spin-Spin Coupling; Solid State NMR Applications in Organotin and Organolead Chemistry; Solid State NMR Investigations of Metal Carbonyl Complexes; High Pressure NMR in Organometallic Chemistry; Multinuclear NMR Spectroscopy in Supercritical Fluids; High Resolution ?6,7Li NMR of Organolithium Compounds; Metal NMR of Organovanadium, -Niobium and -Tantalum Compounds; NMR of Metallic Nuclei in Clusters; ?171Yb NMR Spectroscopy

Roger Bertholf
Chromatographic Methods in Clinical Chemistry and Toxicology

This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications Chromatography has a vast array of clinical applications, and though the chromatographic methods were first introduced decades ago, new applications of this technology are being used to explore previously inaccessible frontiers in clinical diagnostics and toxicological testing An up–to–date book devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text, useful to students, laboratory technicians, and researchers

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